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salvage pathway |
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salvage pathway Oncology A popular term for a metabolic pathway that uses substrates other than the usual biosynthetic intermediates for a product–eg, 1. The salvage of free purines from the hydrolysis of nucleotides for the generation
of new nucleotides, or 2. The 2º pathway of nucleotide synthesis, in which thymidylate is produced by thymidine kinase from thymidine, rather than the usual path in which deoxyuridylate is methylated by thymidylate synthetase into thymidylate,
a pathway utilized by Pts with megaloblastic anemia. See Leucovorin 'rescue.'. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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