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An unconscious defense mechanism used to allay anxiety by denying the existence of important conflicts, troublesome impulses, events, actions, or illness.
Synonym(s): negation
[M.E., fr, O.Fr., fr. L. denegare, to say no]


A denial, contradiction, or negative statement.


An unconscious defense mechanism used to allay anxiety by denying the existence of important conflicts or troublesome impulses.
Synonym(s): negation.
[M.E., fr, O.Fr., fr. L. denego, to say no]

Patient discussion about negation

Q. is her2 positive more agressive than her2 negative? i know someone with her2 positive breast cancer and her doctor said it was more difficult to detect upon its return if it came back i want to know if it is true and what can she do to detect it earlier

A. Over-expression of her2/neu, a specific molecule in the breast cancer cell is indeed considered to convey worse prognosis, and suggest the need for chemotherapy and immunotherapy with Herceptin. However, the decision is much more complicated and should be made on case by case basis after consulting a professional.

Q. Rising PSA to 10 with two negative biospies? Expect cancer? 67 yrs old in good health otherwise.

A. High values don't always mean it's cancer. At 67 years old, you're prostate is most likely enlarging, resulting in the higher PSA results. And after two negative biopsies, it sounds like you're in the clear. Like Brandon said though, keep up with your regular check ups.

Q. Does the cooking have a negative effect on the protein content of the food? I have heard that high temperatures cooking breaks the protein, so does the cooking have a negative effect on the protein content of the food?

A. Yes. Proteins can be denatured by heat, but only when the protein structure is delicate or is exposed to extremely high temperatures for long time. You must remember that breaking of protein is the physical-chemical process where the physical or chemical structure of a protein is rearranged. So cooking will not reduce on the nutritive value of the food until it’s cooked at cooking temperatures.

More discussions about negation
References in periodicals archive ?
Torres' trainer, Orlando Mazara, said that the Yankees told Torres that they would not sign him.
The source said that it is with a heavy heart that Richards has told City that he will not sign a new deal and the club has now accepted that the defender would be leaving, the report added.
Namibia will not sign a 'bad' Economic Partnership Agreement (EPA) that limits its ability to solve domestic developmental agenda problems, the Deputy Minister of Finance, Calle Schlettwein has said.
Girls whose parents signed up were twice as likely to receive their next dose of vaccine within a month of when it was due, compared with their counterparts whose parents did not sign up.
BAGHDAD / Aswat al-Iraq: - Iraqi President Jalal Talabani said on Wednesday he will not sign an execution order for Tareq Aziz, the foreign minister during the former regime who sentenced to death last month over the persecution of Islamic parties.
I will not sign on any working leave before consulting the institution, thus I shall not sign any working permit for a foreign employee replacing the Lebanese employee," Harb added.
The old Republican Congress passed legislation to punish countries that did not sign on the dotted line, even when doing so undermined other foreign policy goals.
Outsourced CFO consultants may not sign checks, bind a company in negotiations or otherwise obligate it for services, but they can provide other important senior financial management.
Dragovic, who will turn 19 in December, will not sign a letter of intent, but he could sign scholarship papers.
He has also confirmed that he did not sign the document.
And he said that even if they offered him a new contract worth pounds 200,000 a week, he would not sign.
SIR - I will not sign the Western Mail health pledge though I broadly agree with its proposals.