diabetic nephropathy (redirected from Nodular glomerulosclerosis)

nephropathy /ne·phrop·a·thy/ (nĕ-frop´ah-the) disease of the kidneys.nephropath´ic

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analgesic nephropathy  interstitial nephritis with renal papillary necrosis, seen with abuse of analgesics such as aspirin or acetaminophen.

diabetic nephropathy  the nephropathy seen in later stages of diabetes mellitus, with first hyperfiltration, renal hypertrophy, microalbuminuria, and hypertension, and later proteinuria and end-stage renal disease.

gouty nephropathy  any of a group of chronic kidney diseases associated with the abnormal production and excretion of uric acid.

HIV-associated nephropathy  renal pathology in patients infected with the human immunodeficiency virus, a condition resembling focal segmental glomerulosclerosis.

IgA nephropathy  see under glomerulonephritis.

ischemic nephropathy  nephropathy resulting from partial or complete obstruction of a renal artery and the accompanying ischemia; there is a significant reduction in the glomerular filtration rate.

membranous nephropathy  see under glomerulonephritis.

minimal change nephropathy  see under disease.

obstructive nephropathy  nephropathy from obstruction of the urinary tract with hydronephrosis and a slowed glomerular filtration rate.

potassium-losing nephropathy  persistent urinary potassium losses in the presence of hypokalemia, such as in metabolic alkalosis or intrinsic renal disease.

reflux nephropathy  childhood pyelonephritis in which the renal scarring results from vesicoureteric reflux, with radiological appearance of intrarenal reflux.

salt-losing nephropathy  any intrinsic renal disease causing abnormal urinary sodium loss to the point of hypotension.

sickle cell nephropathy  chronic kidney disease in sickle cell disease, including vascular abnormalities, fibrosis, and an increased glomerular filtration rate.

urate nephropathy , uric acid nephropathy any of a group of kidney diseases with hyperuricemia, including an acute form, a chronic form (gouty n.), and nephrolithiasis with uric acid calculi.

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diabetic nephropathy (nfro´pthē´),

n the negative effects on the kidneys or renal system caused by diabetes mellitus. The condition may necessitate dialysis or kidney transplant.

diabetic neuropathy,

n the complications to the nervous system that can be caused by diabetes mellitus, some of which may necessitate amputation or result in oral or facial symptoms.

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diabetic nephropathy

Diabetic kidney disease The constellation of renal changes attributed to DM–eg Armanni-Ebstein lesion, arterionephrosclerosis, arteriolonephrosclerosis, chronic interstitial nephritis, diabetic glomerulosclerosis, fatty changes in renal tubules, glomerulonephritis, Kimmelstiel-Wilson disease—focal and segmental glomerulosclerosis, nephrotic syndrome, papillary necrosis, and pyelonephritis; DN is the most common cause of ESRD in the West Diagnosis Microalbuminuria Management Antihypertensives–eg, ACE inhibitors–eg, captopril, protect kidneys against further deterioration in type 1 DM, and a 50% ↓ risk in end points–death, dialysis, and transplantation; if renal failure is in an early stage, the Pts are good transplant candidates; ESRD requires dialysis and protein restriction. See End-stage renal disease.