nitrogen mustard (redirected from Nitrogen mustard compounds)

mustard /mus·tard/ (mus´terd)

1. a plant of the genus Brassica.

2. the ripe seeds of Brassica alba (white mustard) and B. nigra (black mustard), whose oils have irritant, stimulant, and emetic properties.

3. resembling, or something resembling, mustard in one or more of its properties.

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nitrogen mustard 

1. mechlorethamine.

2. any of a group of cytotoxic, blistering alkylating agents homologous to the vesicant war gas dichlorodiethyl sulfide (mustard gas), some of which have been used as antineoplastics and immunosuppressants.

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nitrogen /ni·tro·gen/ (N) (ni´tro-jen) a chemical element, at. no. 7. It forms about 78 per cent of the atmosphere and is a constituent of all proteins and nucleic acids.

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nitrogen 13  a radioactive isotope of nitrogen having a half-life of 9.97 minutes and decaying by positron emission (1.190 MeV); used as a tracer in positron emission tomography.

nitrogen mustard  see under mustard.

nonprotein nitrogen  the nitrogenous constituents of the blood exclusive of the protein bodies, consisting of the nitrogen of urea, uric acid, creatine, creatinine, amino acids, polypeptides, and an undetermined part known as rest nitrogen.

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nitrogen mustard

n.

Any of various toxic blistering compounds analogous to mustard gas but containing nitrogen rather than sulfur, sometimes used to control or check the growth of neoplastic cells.

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nitrogen mustard.

See mechlorethamine hydrochloride.

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nitrogen mustard

Oncology Any of a family of alkylating agents used primarily to treat NHLs,  Hodgkin's disease, ALL, mycosis fungoides; NMs  enter cells via the choline transport system; tumor cells may develop mustard resistance through enhanced repair of alkylated DNA or thiol-mediated mustard inactivation Toxicity GI tract–N&V, myelosuppression with pancytopenia, alopecia, tissue injury, diarrhea, diaphoresis