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nitric oxide |
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nitric /ni·tric/ (ni´trik) pertaining to or containing nitrogen in one of its higher valences.
nitric oxide endothelium-derived relaxing factor; a naturally occurring gas that in the body is a short-lived dilator substance released from vascular endothelial cells in response to the binding of vasodilators; it inhibits muscular contraction and produces relaxation, and is toxic in the central nervous system. A preparation is used in the treatment of persistent fetal circulation in term and near-term neonates. nitric [ni´trik] pertaining to or containing nitrogen in one of its higher valences. nitric acid a highly caustic, fuming acid that has a characteristic choking odor and can be fatal if swallowed. It is sometimes used as a cauterizing agent in the eradication of warts; large amounts of it on the skin can cause necrosis. It is also used in the form of its potassium and sodium salts. The antidote for nitric acid poisoning is liberal application of an alkali or sodium bicarbonate. nitric oxide
1. NO, a naturally occurring gas that in the body is a short-lived dilator released from vascular epithelial cells in response to the binding of vasodilators to endothelial cell receptors; it causes inhibition of muscular contraction, and thus relaxation. Excesses of nitric oxide are toxic to cells of the central nervous system and also cause the drop in blood pressure seen in septic shock. Called also endothelial- or endothelium-derived relaxing factor. 2. a preparation of nitric oxide used together with ventilatory support or other agents in the treatment of respiratory failure due to persistent fetal circulation in term and near-term neonates; administered by inhalation. nitric pertaining to or containing nitrogen in one of its higher valences. nitric acid a highly caustic, fuming acid that has a characteristic choking odor. It was used at one time in the immediate treatment of rabid animal bites to prevent rabies becoming established, and as a cauterizing agent in the eradication of various kinds of warts. It is also used in the form of its potassium and sodium salts. It can be fatal if swallowed, and large amounts of nitric acid applied to the skin can cause necrosis. The antidote for nitric acid poisoning is an alkali or sodium bicarbonate applied liberally. nitric oxide
is produced during the ensiling process and animals in confined spaces and exposed to silo gas may develop severe respiratory disease due to irritation of the alveolar epithelium. Called also silo-filler's disease. See also atypical interstitial pneumonia. nitric oxide A multifaceted bioregulatory agent and environmental pollutant, capable of causing genotoxicity Environment A gas byproduct of high temperature combustion–eg, internal combustion engines which, on exposure to light, results
in NO2 formation, an irritating air pollutant, and major greenhouse gas Physiology Endothelium-derived relaxing factor A neurotransmitter released when glutamate binds to the NMDA receptor, which is critical in regulating vascular tone.
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