Neuroleptic malignant syntrome (NMS) was first reported by Delay and coworkers in 1960 following the introduction of neuroleptic drugs
There are many potential drugs and exogenous agents causing photosensitivity reactions, such as nonsteroidal anti-inflammatory drugs (NSAIDs), antiarrhythmics, antihypertensives, neuroleptic drugs
, antibiotics, retinoids, etc.
Neuroleptic malignant syndrome (NMS) is a rare but life-threatening idiosyncratic side effect resulting from neuroleptic drugs
Neuroleptic Malignant Syndrome (NMS) is an idiosyncratic and potentially life-threatening reaction to neuroleptic drugs
By probing why some patients developed NMS and others not, they identified the administration of neuroleptic drugs
to patients with a catatonic illness as the major culprit.
Though the use of neuroleptic drugs
in alcohol withdrawal is not uncommon, it may be argued that the use of clothiapine is misplaced in a routine regimen.
Other forms of the disease include vascular Parkinsonism, thought to be caused by hypertension and diabetes, drug-induced Parkinsonism, which is most often a result of neuroleptic drugs
used to treat psychotic disorders, and inherited Parkinson's, which is passed through family members.
It is used as an adjunct in the therapy of all forms of parkinsonism and also for the control of extrapyramidal disorders because of neuroleptic drugs
, except tardive dyskinesia.
Tardive dyskinesia is a rare and permanent side-effect of neuroleptic drugs
, which include some of the older antipsychotics as well as some old-fashioned anti-nausea drugs.
The neuroleptic drugs
"induce a brain pathology, similar in kind to encephalitis lethargica and Parkinson's disease.
In response to this body of literature, physicians in Switzerland, Sweden, and Finland developed programs that minimize use of neuroleptic drugs
go by trade names such as Thorazine, Haldol, Seroquel, Zyprexa, Risperdal, and many others.