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neurofilament
(redirected from Neurofilament protein)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
neurofilament /neu·ro·fil·a·ment/ (-fil´ah-ment) an intermediate filament occurring with neurotubules in the neurons and having cytoskeletal, and perhaps transport, functions.
neu·ro·fil·a·ment (nr-fl-mnt)
n.
Any of the long fine threads that make up a neurofibril.

neurofilament
[noo͡r′ōfil′əment]
Etymology: Gk, neuron, nerve + L, filare, to spin
a cytoplasmic filament approximately 10 nm in diameter occurring in the neurons. It has a cytoskeletal function and may be involved in the intracellular transport of metabolites.

neurofilament [noor″o-fil´ah-ment]
any of the slender, fibrillar elements which, along with the neurotubules, forms a neurofibril.

neurofilament
any of the slender, fibrillar elements which, along with the neurotubules, forms a neurofibril.


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Clinical and demographic findings can help make distinctions, as can pertinent immunohistochemical reactions to synaptophysin, chromogranin, neuron-specific enolase (NSE), neurofilament protein (NFP), S-100 protein, keratin, CD45RB, desmin, CD99, and HMB45.
Differential expression of two neuronal intermediate-filament proteins, peripherin and the low-molecular-mass neurofilament protein (NF-L), during development of the rat.
Julien suggests seeking out agents that could block production of the neurofilament protein, but he and others acknowledge that little has been published on the whole topic.
 
 
 
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