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neuraminic acid
(redirected from Neuraminic)

   Also found in: Encyclopedia, Wikipedia 0.03 sec.
neuraminic acid /neu·ra·min·ic ac·id/ (noor″ah-min´ik) a 9-carbon amino sugar whose N- acyl derivatives are the sialic acids.
neu·ra·min·ic acid (nr-mnk)
n.
An aldol condensation product of mannosamine and pyruvic acid and the parent acid of sialic acids.

neuraminic acid
[noor′ah-min′ik]
a nine-carbon amino acid formed from mannosamine and pyruvate. See also sialidase .

sialidase [si-al´ĭ-dās]
1. an enzyme of the hydrolase class that catalyzes the cleavage of glucosidic linkages between a sialic acid residue and a hexose or hexosamine residue at the nonreducing terminal of oligosaccharides in glycoproteins, glycolipids, and proteoglycans. Deficiency of it is an autosomal recessive trait and is seen in sialidosis and galactosialidosis.
2. the enzyme with this activity specifically cleaving sialic acid–containing gangliosides; it is deficient in mucolipidosis IV. Called also neuraminidase.

neuraminic acid
a nine-carbon sugar; parent of a family of amino sugars containing nine or more carbon atoms (the sialic acids or nonulosaminic acids).


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It contains a unique, polymerized glyconutrient ingredient that incorporates all eight essential monosaccharides (glucose, xylose, fucose, N-acetyl galactosmine, mannose, N-Acetyl glucosamine, N-acetyl neuraminic acid and galactose) in a single, non-branched polysaccharide chain.
meningitidis isolates in Canada bore an [alpha] 2-9 N-acetyl neuraminic acid (serogroup C) capsule, but recent epidemics of meningococcal disease, particularly in Africa, have been associated with ST11 meningococci bearing the W135 capsule.
 
 
 
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