Washington, May 27 (ANI): Shark cartilage extract, AE-941 or Neovastat
, has shown no benefit as a therapeutic agent when combined with chemotherapy and radiation for patients with advanced non-small cell lung cancer, say researchers at The University of Texas MD Anderson Cancer Center.
- The Company has decided to terminate its development program being conducted with the National Cancer Institute (NCI) for Neovastat
Its experimental drug, called Neovastat
, is "not like the powdered cartilage that you find in health food stores;' explains company spokesman Paul Burroughs.
c) Reminyl (galantamine Janssen Pharmaceutica HBr) Products LP, Titusville, NJ Neovastat
(AE-941) AEterna Laboratories, Inc.
TSX: AEZ; Nasdaq: AEZS) today announced that following a Data and Safety Monitoring Board recommendation, based solely on a slow patient recruitment rate, the United States National Cancer Institute (NCI) has decided to interrupt patient recruitment for the ongoing Phase III trial in non-small cell lung cancer (NSCLC) with Neovastat
, while awaiting for an interim efficacy data analysis planned at 320 events.
Another NCI-sponsored study evaluating Neovastat
(AE-941), an angiogenesis inhibitor derived from ultrafiltration of liquid dogfish shark cartilage, is ongoing.
Affinitak, Aptosyn, Bevacizumab, Carboxyamidotriazole, Cetuximab, CI-994, Docetaxel, Efaproxyn, Erlotinib, Gefitinib, Gemcitabine, Genasense, Lapatinib IGN-101, Mitumomab, Neovastat
, Paclitaxel, Panitumumab, Pemetrexed, Targretin, Telcyta, Tirapazamine, Trastuzumab, Vinflunine, Vinorelbine, Xcytrin, ZD-6474
New top class drugs such as Angiozyme, BAY 43-9006, Neovastat
, Tarceva, Flavopiridol, PTK787 together with Avastin, Gleevec, Iressa and Erbitux have been included in this progression analysis.
2-methoxyestradiol, AMG-706, ATN-161, AZD-2171, bevacizumab, combretastatin A-4 prodrug, enzastaurin hydrochloride, everolimus, neovastat
, PTK/ZK, sorafenib tosylate, squalamine, thalidomide, vitaxin, XL-999, ZD-6474, volociximab etc.
TSX: AEZ; NASDAQ: AEZS) announced that an interim report of toxicity and response from the ongoing US National Cancer Institute (NCI) Phase III trial in unresectable stage III non-small cell lung cancer with Neovastat
, was presented earlier today by Dr.
Among the most prominent ones Avastin, Neovastat
and Vatalanib can be found.
The year 2003 was exciting but challenging where we had to successfully integrate our two companies on one hand while on the other hand, Neovastat
failed in reaching the primary end point in its phase III renal cell carcinoma trial.