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neoadjuvant chemotherapy

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.03 sec.
chemotherapy /che·mo·ther·a·py/ (-ther´ah-pe) treatment of disease by chemical agents.
adjuvant chemotherapy  cancer chemotherapy employed after the primary tumor has been removed by some other method.
combination chemotherapy  that combining several different agents simultaneously in order to enhance their effectiveness.
induction chemotherapy  the use of drug therapy as the initial treatment for patients presenting with advanced cancer that cannot be treated by other means.
neoadjuvant chemotherapy  initial use of chemotherapy in patients with localized cancer in order to decrease the tumor burden prior to treatment by other modalities.
regional chemotherapy  chemotherapy, especially for cancer, administered as a regional perfusion.

Neoadjuvant chemotherapy
Treatment of the tumor with drugs before surgery to reduce the size of the tumor.
Mentioned in: Neuroblastoma

neoadjuvant chemotherapy
Induction chemotherapy, neoadjuvant therapy, preemptive chemotherapy, primary chemotherapy Oncology 1. The use of chemotherapy on solid–ie, non-hematopoietic neoplasms–eg, osteosarcomas, anal cancer, head&neck cancer; NC is used in Pts with clinically resectable but locally advanced disease that is not amenable to complete eradication surgery or RT; agents used in NC include cisplatin, 5-FU, vinblastine, and the M-VAC 'cocktail.' See Neoadjuvant therapy. Cf Induction therapy.


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27] Thus neoadjuvant chemotherapy needs to be seriously considered in addition to local treatment strategies.
Sinusoidal obstruction syndrome is a major feature of hepatic lesions associated with oxaliplatin neoadjuvant chemotherapy for liver colorectal metastases.
Following a similar approach, Weder mimicked that study when he reported a pilot study where nineteen patients with MME were treated using neoadjuvant chemotherapy followed by EPP with or without consolidating radiotherapy (13).
 
 
 
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