The number of times more likely that a negative test comes from an individual with the disease rather than from an individual without the disease; it is given by the formula: NLR = (1 – Sensitivity) / Specificity.
Diagnostic accuracy of noninvasive parameters in determining esophageal varices with regard to AUC, cutoff value, sensitivity, specificity, positive and negative likelihood ratios, and positive and negative predictive values Parameter AUC Cutoff point Sensitivity 95% CI PC 0.
001 Table 3: Sensitivity, Specificity, Diagnostic Accuracy, Positive Predictive Value (PPV), Negative Predictive Value (NPV), Positive Likelihood Ratio (PLR), Negative Likelihood Ratio (NLR) and Area Under the Curve (AUC) of CRP for the diagnosis of sepsis.
The upper bound of the gray zone is defined by the value of the test associated with the minimal positive likelihood ratio (LR+) that allows ruling in the diagnostic hypothesis, and the lower bound by the maximal negative likelihood ratio (LR-) that allows ruling out the diagnostic hypothesis (Fig.
Negative likelihood ratio of less than one in our study for choledocholithiasis, pancreatico-biliary neoplasia and benign stricture implies significant association between negative test on THI and not having same cause.
Summary measures for sensitivity, specificity, positive likelihood ratio [LR(+)]  negative likelihood ratio [LR(-)], and diagnostic odds ratio (DOR) across the 10 preeclampsia studies were calculated by random-effects ANOVA.