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necrotizing

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.20 sec.
necrotizing /nec·ro·tiz·ing/ (nek´ro-tīz″ing) causing necrosis.
Necrotizing
Causing the death of a specific area of tissue. Human bites frequently cause necrotizing infections.
Mentioned in: Human Bite Infections

necrotizing
[nek′rōtī′zing]
Etymology: Gk, nekros, death
causing the death of tissues or organisms.

necrotizing
causing necrosis; exuding a brown to green, putrid discharge containing tissue debris.

necrotizing epithelioma, necrotizing calcifying epithelioma
necrotizing hepatopancreatitis
disease of shrimps caused by a small obligate intracellular unidentified bacterium; subacute to chronic syndrome with cumulative mortality of up to 90%.
necrotizing panniculitis
multifocal, erythematous, nonpruritic cutaneous lesions which ulcerate in the center and discharge seropurulent exudate; identifiable on histopathological examination.
necrotizing scleritis
a rare eye lesion, inflammatory proliferation of the anterior sclera, in dogs.
necrotizing ulcerative gingivitis
see necrotizing ulcerative gingivitis.
necrotizing vasculitis
important feature of the Arthus reaction; damage to the endothelium results from deposition of immune complexes in the vessel wall, usually on the basement membrane of the endothelium.

Patient discussion about necrotizing.

Q. can necrosis in a brain tumor kill you? If so, how? husband has glioblastoma.Tumor seems under control at this point as much as they can tell but sounds like there is a lot of necrosis. He has lots of tumor progression symptoms but since he has had the tumor for so long == 6 years = I guess the necrosis is there moreso than the actual tumor == how dangerous can this be?

A. Tumors and not only in the brain tend to develop necrosis the longer they exist because the tumor cells divide so rapidly so the blood supply can't keep up with its' own cells demands, so some cells within the tumor die (therefore are seen as necrotic). This does not usually predict prognosis, but only means that the tumor is longstanding.

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