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necrolytic migratory erythema

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
erythema
redness of the skin caused by congestion of the capillaries in the lower layers of the skin. It occurs with any skin injury, infection or inflammation.

erythema ab igne
that due to exposure to radiant heat.
erythema chronicum migrans
the early skin rash at the site of the tick bite which infects humans with Borellia burgdorferi (Lyme disease); rarely seen in dogs.
erythema multiforme
a disease of unknown etiology, but is sometimes drug-related; presumed to be immune-mediated. It occurs in all species and is characterized by an acute onset of erythematous macules, papules, vesicles or bullae. There may also be fever, depression and anorexia.
erythema multiforme major
a rapidly fulminating, ulcerative form of erythema multiforme with involvement of oral mucosa and systemic signs.
necrolytic migratory erythema
in humans, a skin disease associated with glucagon-secreting tumors of the pancreas. The same association has not been observed in dogs, but disease of the liver and pancreas is often present. There are vesicles and crusted, ulcerated lesions, mainly on the face, mucocutaneous areas, distal limbs and feet.
erythema nodosum
a rare disorder in dogs characterized by fever, depression, arthralgia and septal panniculitis.
toxic erythema, erythema toxicum
a generalized erythematous or erythematomacular eruption due to administration of a drug or to bacterial toxins or other toxic substances.

necrolytic migratory erythema
Dermatology A plaque dermatopathy seen on the lower trunk, buttocks, perineum, and thighs of Pts with a glucagonoma of the pancreas Clinical Erythematous, scaling, ± bullous, erosive lesions accompanied by weight loss, anemia, stomatitis Lab ↑ Glucagon. See Glucagonoma.


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Glucagonoma also cause a distinctive skin lesion called necrolytic migratory erythema.
The glucagonoma syndrome includes increased hepatic gluconeogenesis and hyperglycemia, muscle catabolism with associated wasting, and an unusual cutaneous eruption known as necrolytic migratory erythema, sometimes with associated stomatitis or cheilosis.
 
 
 
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