nalbuphine

nalbuphine /nal·bu·phine/ (nal´bu-fēn) an opioid analgesic, used as the hydrochloride salt in the treatment of moderate to severe pain and as an anesthesia adjunct.

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nalbuphine,

a synthetic opioid agonist and antagonist.

indications This drug is used to treat moderate to severe pain.

contraindications Opiate addiction and known hypersensitivity to this drug prohibit its use.

adverse effects Adverse effects of this drug include dysphoria, hallucinations, dreaming, tolerance, physical dependency, psychologic dependency, palpitations, bradycardia, change in blood pressure, orthostatic hypotension, tinnitus, blurred vision, miosis, diplopia, increased urinary output, dysuria, urinary retention, urinary urgency, urticaria, bruising, flushing, diaphoresis, pruritus, and pulmonary edema. Common side effects include drowsiness, dizziness, confusion, headache, sedation, euphoria, nausea, vomiting, anorexia, constipation, cramps, and rash. Respiratory depression is a life-threatening side effect.

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analgesic [an″al-je´zik]

1. relieving pain.

2. pertaining to analgesia.

3. an agent that relieves pain without causing loss of consciousness.

narcotic analgesic opioid analgesic.

nonsteroidal antiinflammatory analgesic (NSAIA) nonsteroidal antiinflammatory drug.

opiate analgesic (opioid analgesic) any of a class of compounds that bind with a number of closely related specific receptors (opioid receptors) in the central nervous system to block the perception of pain or affect the emotional response to pain; such compounds include opium and its derivatives, as well as a number of synthetic compounds, and are used for moderate to severe pain. Chronic administration or abuse may lead to dependence.

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nalbuphine

a potent synthetic narcotic agonist-antagonist used as the hydrochloride for relief of moderate-to-severe pain.

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nalbuphine

Nubain^® A synthetic narcotic chemically related to naloxone and similar in action to, but less addictive than, morphine, it has a similar analgesic intensity as morphine, but has a ceiling on the intensity of the respiratory depression it causes when in excess Adverse effects Sweating, N&V, vertigo, dry mouth, headache