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Naked DNA

   Also found in: Wikipedia 0.01 sec.
Naked DNA
A purified DNA sequence with no associated proteins. An immune response can be evoked by directly injecting into the host DNA that encodes an immunogen of interest
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DNA constructs encoding a chimeric T-cell receptor and a method of making a redirected T cell expressing a chimeric T cell receptor by electroporation using naked DNA encoding the receptor are also disclosed.
City of Hope obtains United States patent by BIOTECH Patent News
After an introductory article on DNA vaccines contributors offer such topics as the regulatory aspects of DNA as a pharmaceutical, plasmid manufacturing and storage, localized nucleic acid delivery, needle-less injection of naked DNA for nonviral in vivo gene transfer, inhalation, hydrodymanic gene delivery, applications to skin diseases, electrotransfection, electrogenetransfer, and a clinical study of cancer inhibition in mice.
DNA pharmaceuticals: Formulation and Delivery in Gene Therapy, DNA ... by SciTech Book News
NAKED DNA If viral vectors are risky and nonviral vectors are difficult to develop, why not get rid of the carrier altogether?
Delivering the goods: gene therapy without the virus by Gorman, Jessica / Science News
 
 
 
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