NRAMP

(redirected from NRAMP1)
Also found in: Acronyms.

NRAMP

A protein of the solute carrier family 11, encoded by SLC11A1 on chromosome 2q35, which transports iron and other divalent metals (e.g., manganese, cobalt, zinc, cadmium and lead) across the apical membrane of enterocytes in the brush border of the GI mucosa and into cells by a proton-coupled process.
 
Abnormal in
Mutations of SLC11A1 have been associated with increased susceptibility to infections (e.g., tuberculosis and leprosy), and inflammatory diseases (e.g., rheumatoid arthritis and Crohn’s disease).
References in periodicals archive ?
Statistical analysis between the polymorphisms of the NRAMP1 gene and the immune traits were performed using PROC MIXED of SAS9.
To determine tissue distribution of the porcine NRAMP1 gene, reverse transcription quantitative PCR (RT-PCR) was applied on nine different tissues of samples.
657 A>G) in intron1 region of the porcine NRAMP1 gene.
Association analysis of porcine NRAMP1 gene in four pig populations
3'UTR polymorphisms in the NRAMP1 gene are associated with susceptibility to tuberculosis in Koreans.
n] polymorphism at 3'UTR of NRAMP1 with the macrophage function following challenge with Brucella LPS in buffalo (Bubalus bubalis).
A complex pattern of microsatellite polymorphism within the bovine NRAMP1 gene.
13] microsatellite allele at 3'UTR of NRAMP1 gene in Indian zebu (Bos indicus) and crossbred (Bos indicusxBos taurus) cattle.
Complete nucleotide sequence and genomic structure of the human NRAMP1 gene region on chromosome region 2q35.
Resistance to salmonellosis in the chicken is linked to NRAMP1 and TNC.
Structural organization, sequence and expression of the chicken NRAMP1 gene encoding the natural resistance associated macrophage protein 1.
Identification of a highly polymorphic length variant in the 3'UTR of NRAMP1.