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Plasma NPY concentrations were detected for all of the participants in the supine position.
mRNA expression of LEPR, JAK2, STAT3, NPY, KISS1 and TRPC5 in hypothalamus tissue
NPY has been shown to be a potent orexigenic agent in chickens when administered centrally (Kuenzel and McMurtry, 1988).
Central administration of NPY or an NPY-Y5 selective agonist increase in vivo extracellular monoamine levels in mesocorticolimbic projecting areas.
The half-life of NPY is approximately 20 min (30), while the half-life of CART peptide is between 40 and 60 min (31).
It is thus of interest that acute intense exercise induces NPY release in healthy humans [28-29] and that rodents show acute increases in plasma and brain allopregnanolone levels after acute swim stress [30-33].
Esta accion aumenta la sintesis y secrecion de NPY y la AgRP, ambos potentes orexigenicos.
GBAN bp ACTB se, 5'-AGCCATGTACGTAGCCATCC-3' NM_031144 115 as, 5'-ACCCTCATAGATGGGCACAG-3' LEP se, 5'-GAGACCTCCTCCATCTGCTG-3' NM_013076 192 as, 5'-CTCAGCATTCAGGGCTAAGG-3' NPY se, 5'-TACTCCGCTCTGCGACACTA-3' NM_012614 115 as, 5'-GGGCATTTTCTGTGCTTTCT-3' se: sense; as: antisense; GBAN: GenBank Accession Number; amplicon length, in bp.
Three groups of seven rats were treated as follows: group 1 [saline + saline (SF + SF)] 1 ml saline ip; group 2 [(saline + PTZ (SF + PTZ)] 1 ml saline ip 30 min before PTZ; and group 3 (NPY + PTZ) 60 [micro]g/kg NPY ip 30 min before PTZ [13, 14].
To evaluate the effects of sexual maturation on sbGnRH and NPY gene expression, five juvenile male fish (71.
In vivo, chronic stress, consisting of cold water or aggression in HFS-fed mice, stimulates the release of NPY and the expression of Y2Rs in visceral fat, increasing its growth by 50% in 2 weeks.
An imbalance of NPY signaling at a local level [the arcade nucleus (ARC) and PVN] results in unregulated eating (Kalra & Kalra 2004b).
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- NPY-Y2 receptor