Randomized cross-over trial of insulin glargine plus lispro or NPH insulin
plus regular human insulin in adolescents with type 1 diabetes on intensive insulin regimens.
Meta-analysis of maternal and neonatal outcomes associated with the use of insulin glargine versus NPH insulin
A potential major advantage of insulin glargine over NPH insulin
and ultralente preparations is a lack of pronounced peaks in plasma insulin concentrations and a more constant delivery of insulin over a 24 hour period.
He self-adjusted his NPH insulin
dosage according to whether he was using 4.
In addition, a randomized trial demonstrated the addition of either insulin glargine or NPH insulin
to oral therapy is effective in achieving target AlC values of 7% (Riddle, Rosenstock, Gerich, & Insulin Glargine 4002 Study Investigators, 2003).
In the past, basal insulin such as NPH insulin
has been problematic, because it has a peak in activity often requiring either inadequate dosing or supplemental glucose (4).
In isoglycaemic clamp studies, insulin detemir has demonstrated improved pharmacokinetic and pharmacodynamic activity combined with improved within-patient variability compared with NPH insulin
(11-13), or insulin glargine (11,14).
Pharmacokinetics and pharmacodynamics of subcutaneous injection long-acting human insulin analogue glargine, NPH insulin
and ultralente human insulin and continuous subcutaneous infusion of insulin lispro.
Some people who take a noon shot still do better with a small amount of NPH insulin
in the morning," he said.
Patients on once-daily NPH insulin
or Ultralente can be switched to the same dose of Lantus.
Amanda's pre-camp insulin dose was 25 units NPH insulin
and 15 units Regular insulin before breakfast and 15 units NPH insulin
and 8 units Regular insulin before supper (1.