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NMDA receptor

   Also found in: Wikipedia 0.03 sec.
NMDA receptor (nmd)
n.
A brain receptor activated by the amino acid glutamate, which when excessively stimulated may cause cognitive defects in Alzheimer's disease. Also called N-methyl-d-aspartate receptor.


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NMDA receptors control the movement of calcium in and out of brain cells, which is necessary for normal brain function.
PSD-95/SAP90 appears to mediate the role of the NMDA receptor in determining the MAC of inhalational anesthetics.
In work published in the Proceedings of the National Academy of Sciences, the team has found NMDA receptors are essential in modifying brain oscillations - electrical wave patterns - which are altered in patients with schizophrenia.
 
 
 
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