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NMDA antagonist

   Also found in: Wikipedia 0.01 sec.
NMDA antagonist
Neurology Any of a number of agents that protect against brain damage in neurologic disorders–eg, stroke; PCP–phencyclidine and ketamine are effective, but have psychotomimetic effects or damage neurons in the cerebral cortex; diazepam and barbiturates act at the GABA receptor channel complex, and may prevent the unwanted side effects of NMDA antagonists


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POSSIBLE DRUG DRUG NAME INTERACTIONS Namenda[R] (memantine) Other NMDA antagonist medications, Blocks the toxic effects including amantadine, an antiviral used to associated with excess treat the flu, dextromethorphan, prescribed glutamate and regulates to relieve coughs due to colds or flu, and glutamate activation.
It may be that in a dosing regimen such as was used in our study, there's an accumulation of D-cycloserine--which causes it to switch from being an NMDA receptor agonist to an NMDA antagonist, as has been shown in animal studies," Dr.
2+] ions, while a second fraction did not possess NMDA antagonist activity despite the presence of ~4 mM magnesium suggesting that [Mg.
 
 
 
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