NLRC4


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Related to NLRC4: Lrp4

NLRC4

A gene on chromosome 2p22-p21 that encodes a protein which self-associates, binds to ASC, pro-caspase-1, NOD2, BCL10 and NALP1 by CARD-CARD interaction, and promotes apotosis.
References in periodicals archive ?
AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3," Proceedings of the National Academy of Sciences, vol.
Bacterias intracelulares, como Salmonella typhimurium, Legionella pneumophila y Burkholderia thailandensis pueden ser detectadas por el inflamasoma NLRC4, el cual es activado por la flagelina (55).