NHL


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.

NHL

Abbreviation for non-Hodgkin lymphoma.

Non-Hodgkin's lymphoma (NHL)

[- hoj′kənz]
solid tumors of peripheral lymphoid tissue classified by histological features and lymphocyte morphology. Distinguished from Hodgkin's lymphoma, a proliferation of Reed-Sternberg cells with accumulation of reactive peripheral blood cells. Non-Hodgkin's lymphoma prevalence peaks at 50 years of age and may be mild or aggressively malignant, depending upon cell category. Once called lymphosarcoma or sarcoma.
enlarge picture
Non-Hodgkin's lymphoma

NHL

Non-Hodgkin's lymphoma, see there.

lymphoma

(lim-fo'ma ) ('mat-a) plural.lymphomaslymphomata [ lymph- + -oma]
A malignant neoplasm originating from lymphocytes. Common forms of lymphoma are listed in the subentries below. These include Hodgkin disease, mycosis fungoides, and non-Hodgkin lymphoma.lymphomatous ('mat-us), adjective See: Hodgkin disease

Staging

Staging of both Hodgkin and non-Hodgkin lymphoma is as follows: Stage I: involvement of a single lymph node or localized involvement. Stage II: Involvement of two or more lymph node regions on the same side of the diaphragm. Stage III: Involvement of several lymph node regions on both sides of the diaphragm. Stage IV: Involvement of extralymphatic tissue, such as the bone marrow.

anaplastic large cell lymphoma

Abbreviation: ALCL
A rare form of non-Hodgkin, T-cell lymphoma that may behave indolently when limited to the skin or may be more aggressive and spread to lymph nodes throughout the body.

body cavity lymphoma

Primary effusion lymphoma.

Burkitt lymphoma

See: Burkitt lymphoma
Enlarge picture
CUTANEOUS T-CELL LYMPHOMA: Raised reddish-purple plaque on the skin of the hip

cutaneous T-cell lymphoma

Abbreviation: CTCL.
A malignant non-Hodgkin lymphoma with a predilection for infiltrating the skin. In its earliest stages, it often is mistaken for a mild, chronic dermatitis because it appears as itchy macules and patches, often on the chest or trunk. Later, the lesions may thicken, become nodular, or spread throughout the entire surface of the skin, the internal organs, or the bloodstream.
See: illustration

follicular lymphoma

A B-cell, non-Hodgkin lymphoma found in adult and older patients. It results from a translocation of an oncogene from chromosome 14 to chromosome 18 [t(14; 18)]. Most instances of this lymphoma are indolent or slow growing.

hepatosplenic T-cell lymphoma

A rare, rapidly progressive lymphoma that develops in the liver, spleen, and bone marrow. It has been identified in patients taking immunosuppressive drugs for diseases such as inflammatory bowel disease.

Hodgkin lymphoma

See: Hodgkin, Thomas

Mediterranean lymphoma

Immunoproliferative small intestinal disease.
Enlarge picture
NON-HODGKIN LYMPHOMA: Bizarre-appearing lymphocytes revealing active mitosis (orig. mag. ×1000)

non-Hodgkin lymphoma

Abbreviation: NHL
Any of a group of malignant tumors of B or T lymphocytes. In 2008, the American Cancer Society estimated that about 66,100 Americans would be newly diagnosed with the disease. See: illustration; Hodgkin disease

Symptoms

Painless lymphadenopathy in two thirds of patients is the most frequent presenting symptom. Others have fever, night sweats, and loss of 10% or more of body weight in the 6 months before presenting with symptoms of infiltration into nonlymphoid tissue. Additional involvement is in peripheral areas such as epitrochlear nodes, the tonsillar area, and bone marrow. NHL is 50% more frequent in occurrence in men than in women of similar age. In most cases the cause of NHL is unknown, but patients who have received immunosuppressive agents have an over 100 times greater chance of developing NHL, probably because the immunosuppressive agents activate tumor viruses.

Treatment

Specific therapy depends on the type, grade, and stage of the lymphoma. Combination chemotherapies, bone marrow transplantation, radiation therapy, and photochemotherapy may be given, depending on the specific diagnosis.

primary effusion lymphoma

A non-Hodgkin B-cell lymphoma that typically arises in body cavities such as the pleural, peritoneal, or pericardial spaces. It is caused by Kaposisarcoma herpesvirus (human herpes virus 8) and is usually found in patients with advanced immune suppression.
Synonym: body cavity lymphoma
Enlarge picture
NON-HODGKIN LYMPHOMA: Bizarre-appearing lymphocytes revealing active mitosis (orig. mag. ×1000)

non-Hodgkin lymphoma

Abbreviation: NHL
Any of a group of malignant tumors of B or T lymphocytes. In 2008, the American Cancer Society estimated that about 66,100 Americans would be newly diagnosed with the disease. See: illustration; Hodgkin disease

Symptoms

Painless lymphadenopathy in two thirds of patients is the most frequent presenting symptom. Others have fever, night sweats, and loss of 10% or more of body weight in the 6 months before presenting with symptoms of infiltration into nonlymphoid tissue. Additional involvement is in peripheral areas such as epitrochlear nodes, the tonsillar area, and bone marrow. NHL is 50% more frequent in occurrence in men than in women of similar age. In most cases the cause of NHL is unknown, but patients who have received immunosuppressive agents have an over 100 times greater chance of developing NHL, probably because the immunosuppressive agents activate tumor viruses.

Treatment

Specific therapy depends on the type, grade, and stage of the lymphoma. Combination chemotherapies, bone marrow transplantation, radiation therapy, and photochemotherapy may be given, depending on the specific diagnosis.

See also: lymphoma
References in periodicals archive ?
And as the NBA did with the Dream Team, the NHL will join the Olympics in February, pitting the best professional hockey players in the world against each other for two weeks, right before most of them return to their respective NHL teams.
com unveiling, the NHL also announced today that it is the first sports league to collaborate with Yahoo
The transport agreement between the two companies ensures that NHL Network will be available to all IP-PRIME operators throughout United States.
So that's our great chance, and I think that's a reason the NHL is supplying players for the Olympics.
NHL is the fifth-leading cause of cancer deaths in the United States (23,400 estimated in 2003) and the sixth-leading cause of cancer deaths in Canada (2,800 estimated in 2003), according to estimates of the American Cancer Society and the Canadian Cancer Society.
Throughout the NHL season, Discover will offer opportunities for cardmembers to redeem their Cashback[R] Bonus rewards for tickets to the 2012 Bridgestone NHL Winter Classic[R] in Philadelphia.
The NHL definitely will swim as a big fish in OLN's small pond - OLN is in 64 million homes, about 25 million fewer than ESPN and ESPN2.
Schering AG, Germany is currently investigating the use of ZEVALIN in the treatment of aggressive NHL (i.
In the 1990s, the increasing incidence of NHL also leveled off in Denmark (study period 1989-1998; Danish Cancer Registry 2002) and in Finland (study period 1954-2000; Finnish Cancer Registry 2003), but not in Norway (1955-2000; Cancer Registry of Norway 2003) or in the United Kingdom (1971-1997; National Statistics 2001).
The newest NHL SKATE facilities will join NHL SKATE at Birch Run, MI, which has entertained more than a quarter million people since its opening in September 1997, and NHL SKATE at Danbury, CT, which will open in September 1999.
Reebok's Sports Licensed Division (SLD), the authentic outfitter of the National Hockey League (NHL), today announced a unique partnership with Champs Sports to establish it as a pinnacle retail destination for the NHL in both Canada and the United States.