The c-Jun NH2-terminal
kinase is activated by multiple forms of stress and has been proven to be a mediator of stress-induced apoptosis.
5-Fluorouracil blocks transforming growth factor-beta-induced alpha 2 type I collagen gene (COLIA2) expression in human fibroblasts via c-Jun NH2-terminal
kinase / activator protein-1 activation.
Ceramide promotes apoptosis in lung cancer-derived A549 cells by a mechanism involving c-Jun NH2-terminal
Selective deletion of the NH2-terminal
variable region of cardiac troponin T in ischemia reperfusion by myofibril-associated mucalpain cleavage.
Stark, On the reversible reaction of cyanate with sulfhydryl groups and the determination of NH2-terminal
cysteine and cystine in proteins, J.
Prognostic value of NH2-Terminal
pro B-type Natriuretic peptide in patients with diabetes and stable coronary heart disease.
Stabilizing the long NH2-terminal
helix pair of GrpE by an engineered disulfide bond abolishes the thermal transition in GrpE and reduces the deviation of the ADP/ATP exchange activity of GrpE from an Arrhenius temperature dependence, indicating that the long helix pair acts as the primary thermosensor of the chaperone system.
Reactive oxygen species-dependent c-Jun NH2-terminal
kinase/c-Jun signaling cascade mediates neuroblastoma cell death induced by diallyl disulfide.
Wherein the NH2-terminal
CUB domain (CUB1) is encoded by exons 2 and 3, whereas the second CUB domain (CUB2) is encoded by exons 4 and 5 and by part of exon 6.
Structural relationship between "glutamic acid" and "lysine" forms of human plasminogen and their interaction with the NH2-terminal
activation peptide as studied by affinity chromatography.
CYANIDIN 3-GLUCOSIDE PROTECTS 3T3-L1 ADIPOCYTES AGAINST H2O2-OR TNF-ALPHA-INDUCED INSULIN RESISTANCE BY INHIBITING C-JUN NH2-TERMINAL
It is well known that the NH2-terminal
regions of LT and CT exhibit the highest degree of homology (91%), while the COOH-terminal region, containing the sole cystine residue in each toxin is less conserved (~52%).