NDM-1

NDM-1

New Dehli metallo-beta-lactamase 1. A recently-identified gene mutation which is responsible for a new class of drug-resistant superbacteria (”superbugs”). First isolated from medical tourists who had returned to Great Britain after having plastic surgery in India or Pakistan, the NDM-1 mutation has been identified in bacteria (e.g., Klebsiella pneumoniae and E. coli) in patients in Australia, Britain, Canada and the US, and has been associated with urinary tract infections, bacteraemia and pneumonia. It is resistant to virtually all antibiotics.
References in periodicals archive ?
aeruginosa strains expressing RmtC with and without an intact ISEcp1 element and NDM-1 is of major clinical concern and calls for further studies to limit the spread of such strains.
It was soon detected throughout South Asia, and most patients infected by bacteria with NDM-1 have had an epidemiological link to South Asian countries.
NDM-4 detected at Aligarh is a more deadly variant of the New Delhi metallo lactamase NDM-1 first isolated from a Swedish patient of Indian origin in 2009.
As we observed that out of 15 NDM-1 positive isolates, only five showed the presence of Sul-1-type integrons indicating that probably in our study isolates, NDM-1 (along with combination of other [bla.
Through a striking finding, a group of Canadian researchers from McMaster University has discovered a chemical compound known as AMA which can turn off an evil gene called New Delhi Metallo-beta-Lactamase-1, or NDM-1.
The first case of NDM-1 carbapenem resistance in South Africa (SA) occurred in August 2011 [3] and was reported from a hospital in Johannesburg.
coli, NDM-1 and ESCAPE pathogens, with an overall contact time of four minutes.
April 9, 2013 /PRNewswire/ -- Smith & Nephew (LSE: SN, NYSE: SNN), the global medical technology business, today announced in-vitro study results suggesting ACTICOAT Silver-Coated Antimicrobial Dressings are bactericidal against some antibiotic resistant organisms carrying the NDM-1 enzyme, often referred to as 'superbugs'.
She says the problem has arisen because of a lack of new drugs so that threats including NDM-1, VRSA and C.
Since NDM-1 is found in Gram-negative bacteria like K.
In addition to the growing problem of antibiotic resistance, Cardiff University research identified the NDM-1 gene in New Delhi, India, which makes bacteria resistant to multiple antibiotics.
NDM-1 stands for New Delhi metallo-beta-lactamase-1 -- first identified in a patient who had been in a hospital in New Delhi, India, in 2008.