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Assessing DNA copy number, messenger RNA expression, and focused exon resequencing in 218 prostate cancer tumors, the authors identified the role of nuclear receptor coactivator NCOA2 as a novel oncogene in 11% of PCa cases.
ACOXI, the human peroxisomal acylcoenzyme A oxidase, is hypothesized in the model to upregulate both RARI3 and NCOA2.
The only other linkage that did not appear to be supported by these data was the hypothesized linkage between NCOA2 and ZNF42.
Assessing DNA copy number, mRNA expression, and focused exon resequencing in 218 PCa tumors, the authors (74) identified the role of nuclear receptor coactivator NCOA2 as a novel oncogene in 11% of PCa cases.
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- NCO Group
- NCO I/C
- NCO LANT
- NCO Leaders Skill Inventory
- NCO MED
- NCO PAC
- NCO/IT R&D