IL13

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IL13

A gene on chromosome 5q31 that encodes interleukin-13, an immunoregulatory cytokine produced primarily by activated Th2 cells which is involved in B-cell maturation and differentiation. IL13 upregulates CD23 and MHC class II expression and promotes IgE isotype switching in B cells; it downregulates macrophage activity, inhibiting production of pro-inflammatory cytokines and chemokines.

Molecular pathology
IL-13 plays a central in the pathogenesis of allergen-induced asthma by IgE- and eosinophil-independent mechanisms.
References in periodicals archive ?
As a general rule, if outlets are selected for a sound level of NC30 or less and at least 10 ft (3 m) apart, the sound levels should not be additive.
For extra cover-up, neutralise the bluey-reddish undertones with a yellow-based concealer, such as MAC Select Cover-up in NC30, pounds 11.
Scottish raider Rab Davies took two victories and two second places aboard his NC30 Honda with Simon Glennie (Kawasaki ZXR) another victor in the class.
The BU-50H is an extremely quiet P/T system and features a maximum noise level of NC30.
Apenas nas Alpinas houve influencia do NC, sendo que as que receberam NC30 produziram mais leite em relacao as NC60, o que pode ser explicado pelo maior potencial de producao das cabras NC30, devido ao elevado numero de cabras com maior ordem de paricao nesse tratamento, afinal fisiologicamente, cabras de primeira paricao ainda nao possuem o sistema mamario totalmente desenvolvido e consequentemente apresentam uma menor producao (3).
Leyburn's James Brackenbury finished in 22nd place aboard his GSXR 1000 Suzuki, with Darlington's Graham Walker one place behind aboard his little NC30 400cc Honda.
Designers may develop firmware using Mitsubishi's NC30WA integrated C-compiler package, which includes the NC30 C compiler, AS30 assembler, and TM tool manager integrated development environment.