CYBB

(redirected from NADPH oxidase 2)

CYBB

A gene on chromosome Xq21.1 that encodes the cytochrome b beta chain, which is a primary component of the microbicidal oxidase system of phagocytes
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Artesunate promoted anti-oxidant catalase activity and reduced NADPH oxidase 2 (NOX2) protein level in the lungs from cigarette smoke-exposed mice.
The protective effects exhibited by artesunate may be associated with inhibition of phosphoinositol 3-kinase (PI3K) and p44/42 mitogen-activated protein kinase (MAPK) pathways, augmentation of Nrf2 expression and catalase activity, and down-regulation of NADPH oxidase 2 (NOX2) expression.