NAD+ synthetase

NAD+ syn·the·tase

an enzyme that catalyzes the reaction of ATP, l-glutamine, and nicotinate adenine dinucleotide to form NAD+, ADP, and l-glutamate.
References in periodicals archive ?
The NAD+ synthetase enzyme that our study describes is absolutely essential for the survival of the tuberculosis bacteria and an important drug target.
The researchers point out that NAD+ synthetase is responsible for making NAD+, a coenzyme found in all living cells that is involved in regulating many cellular processes and in reduction-oxidation metabolic reactions.
In humans, according to the team, NAD+ can be obtained through several different complex pathways, and not all of the pathways utilize NAD+ synthetase to produce NAD+.
However, there are only two pathways involved in producing NAD+ in the tuberculosis bacterium, and both depend on the activity of NAD+ synthetase to obtain NAD+.