NMDA receptor

(redirected from N-methyl-D-aspartate receptor)
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NMDA re·cep·tor

a type of glutamate receptor that participates in excitatory neurotransmission and also binds N-methyl-d-aspartate; may be particularly involved in the cell damage observed in individuals with Huntington disease.

NMDA receptor

A brain receptor activated by glutamate, which when excessively stimulated may cause cognitive defects in Alzheimer's disease.
References in periodicals archive ?
Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels become reduced.
Kynurenic acid and quinolinic acid act at N-methyl-D-aspartate receptors in the rat hippocampus.
The four main families of excitatory amino acid receptors are [alpha]-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPA), N-methyl-D-aspartate receptors (NMDA), metabotropic glutamate receptors, and kainic acid receptors.
Scientists previously had developed a model where N-methyl-D-aspartate receptors control the flow of calcium into signal-receiving neutrons.

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