glycosylation

(redirected from N-linked glycosylation)
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glycosylation

 [gli-ko″-sĭ-la´shun]
the formation of linkages with glycosyl groups.

gly·co·sy·la·tion

(glī'kō-si-lā'shŭn),
Formation of linkages with glycosyl groups, as between d-glucose and the hemoglobin chain to form the fraction hemoglobin AIc, the level of which rises in association with the elevated concentration of d-glucose in blood concentration in poorly controlled or uncontrolled diabetes mellitus.
See also: glycosylated hemoglobin.

glycosylation

/gly·co·syl·a·tion/ (gli-ko″sĭ-la´shun) the formation of linkages with glycosyl groups.

glycosylation

(glī′kō-sĭ-lā′shən)
n.
The addition of saccharides to proteins or lipids to form a glycoprotein or glycolipid.

gly·co′sy·late′ v.

glycosylation

[glīkə′səlā′shən]
the formation of linkages with glycosyl groups, covalently attaching a carbohydrate to another molecule.

gly·co·sy·la·tion

(glī'kō-si-lā'shŭn)
Formation of linkages with glycosyl groups, as between d-glucose and the hemoglobin chain to form the fraction hemoglobin AIc, the level of which rises in association with the raised blood d-glucose concentration in poorly controlled or uncontrolled diabetes mellitus.
See also: glycosylated hemoglobin

glycosylation

the addition of a CARBOHYDRATE to an organic molecule such as a PROTEIN.

glycosylation (glī·kōˈ·s·lāˑ·shn),

n process in which a carbohydrate is covalently attached to another molecule.

glycosylation

the formation of linkages with glycosyl groups.

N-linked glycosylation
attachment of oligosaccharides, synthesized on a dolichol-lipid platform to proteins through the amino acid asparagine spaced close to threonine or serine in the polypeptide sequence.
O-linked glycosylation
attachment of groups of oligosaccharides directly to proteins through the hydroxyl group of threonine.
References in periodicals archive ?
EX-CELL Glycosylation Adjust (Gal+) is an off-the-shelf protein quality supplement designed to achieve functionally relevant shifts in N-linked glycosylation quickly and efficiently, according to the company, and is highly concentrated, only requiring a small amount of product.
Effect of N-linked glycosylation on biological activity.
Effects of disulfide bond formation on N-linked glycosylation and secretion.
Each has multiple cysteine residues, [TABULAR DATA FOR TABLE I OMITTED] and one potential N-linked glycosylation site ([Asn.
N-linked glycosylation was investigated using MALDI-TOF MS of both the full-length native attractin and the reduced and alkylated attractin.
This result is consistent with N-linked glycosylation (Figure 3, panel B).
Metabolic mimics: the disorders of N-linked glycosylation.
Building on data derived from these methods, Aebersold's group (103) developed a searchable online catalog for depositing data regarding N-linked glycosylation sites and glycopeptide sequences (www.
1]-antitrypsin leads to the loss of a sequon for N-linked glycosylation, i.
Only 1 potential N-linked glycosylation site was conserved at the junction of the intracellular and transmembrane domains.
A substitution of amino acid isoleucine for asparagine at position 20 of the G protein added a potential glycosylation site apart from the eight identified N-linked glycosylation sites (6).