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myeloproliferative
(redirected from Myeloproliferative disease)

   Also found in: Dictionary/thesaurus, Wikipedia 0.02 sec.
myeloproliferative /my·elo·pro·lif·er·a·tive/ (-pro-lif´er-ah-tiv) pertaining to or characterized by medullary and extramedullary proliferation of bone marrow constituents; see under disorder.
my·e·lo·pro·lif·er·a·tive (m-l-pr-lf-rtv)
adj.
Relating to or characterized by unusual proliferation of myelopoietic tissue.

myeloproliferative
pertaining to or characterized by abnormal proliferation of bone marrow constituents.

myeloproliferative disease
a group of diseases related histogenetically and marked, at varying times in varying degrees, by medullary and extramedullary proliferation of one or more lines of bone marrow constituents, including myelocytic, erythroblastic and megakaryocytic forms, in addition to various cells derived from the reticulum and mesenchymal elements. It occurs most commonly in cats, often associated with feline leukemia virus infection, causing anemia, weight loss, fever and hepatosplenomegaly. Hematological findings usually include the presence of abnormal cells, corresponding to the proliferating cell type. The forms seen include erythremic myelosis, reticuloendothelosis, myeloid leukemia, erythroleukemia, monocytic leukemia, myelomonocytic leukemia, megakaryocytic myelosis and eosinophilic leukemia.


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