myelin-associated glycoprotein


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myelin-associated glycoprotein

A glycoprotein in myelin of central and peripheral nervous systems. Anti-MAG antibodies are detected in 50% of patients with IgM paraproteinemia and peripheral neuropathy, and may occur in some patients with multiple sclerosis, Guillain-Barré syndrome, chronic polyneuropathy or myasthenia gravis.
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Blockade of Nogo-66, myelin-associated glycoprotein, and oligodendrocyte myelin glycoprotein by soluble Nogo-66 receptor promotes axonal sprouting and recovery after spinal injury.
Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth.
Treatable gait disorder and polyneuropathy associated with high titer serum IgM binding to antigens that copurify with myelin-associated glycoprotein.
Oakland, NJ) - "SMAGALS: Stop Myelin-Associated Glycoprotein (MAG) for Amyotrophic Lateral Sclerosis (ALS): A futuristic approach to the treatment of Amyotrophic Lateral Sclerosis (ALS) that combines a special pump and a combination of drugs utilizing "buckyballs" to deliver a special antibody into the spinal fluid.
In mammals, several myelin-associated factors such as myelin-associated glycoprotein (MAG), oligodendrocyte myelin glycoprotein (OMgp) and Nogo inhibit the regeneration of axons in the CNS.
1994) Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth.