Because of the DNA's tweaked structure, the myelin basic protein
that these cells then produce isn't seen as an enemy, and other immune cells decrease their responses against it.
This infection should activate the CD8+T cells to first attack the virally infected cells making myelin basic protein
to eliminate the virus, then kill other cells that make myelin basic protein
to wrap around nerves.
Protein S-10013, neuron-specific enolase (NSE), myelin basic protein
(MBP) and glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and blood of neurological patients.
MBP8298 (dirucotide) is a synthetic peptide that consists of 17 amino acids having a sequence identical to that of a portion of human myelin basic protein
Age related changes of neuron-specific enolase, S-100 protein, and myelin basic protein
concentrations in cerebrospinal fluid.
In the process, he founded a biotechnology company called AutoImmune, which conducted trials for Myloral, or oral myelin basic protein
, for people with MS, as well as similar substances for diabetes and rheumatoid arthritis.
Some of those cells can target myelin basic protein
, a component of myelin, but nonetheless seem to ignore its presence.
Myelin basic protein
(MBP) is the major protein component of myelin (1), and the concentration of MBP or its fragment in cerebrospinal fluid (CSF), as measured by a RIA, correlates closely with the clinical activity of MS and other diseases in which there is myelin breakdown (2-8).
Copaxone or copolymer 1 (now known generically as glatiramer acetate for injection) is a synthetic protein that simulates myelin basic protein
, a component of the material called myelin that insulates nerve fibers in the brain and spinal cord.
They found that very low doses of myelin basic protein
(MBP)--a protein found on the myelin sheath that covers nerves in the brain and spinal cord--suppressed the autoimmune attack on the brain.
We also tested for cross-reactivity with myelin basic protein
White blood cells that react against myelin, specifically against a major component called myelin basic protein
, were discovered in the animal form of MS, called EAE (experimental autoimmune encephalomyelitis) and in human MS.