mycosis fungoides

mycosis /my·co·sis/ (mi-ko´sis) any disease caused by fungi.

---

mycosis fungoi´des  a chronic, malignant, lymphoreticular neoplasm of the skin and, in late stages, lymph nodes and viscera, with development of large, painful, ulcerating tumors.

---

mycosis fun·goi·des (fng-goidz)

n.

A chronic progressive lymphoma arising in the skin and initially simulating an inflammatory dermatosis.

---

Mycosis fungoides

The most common type of cutaneous T-cell lymphoma. This low-grade lymphoma primarily affects the skin. Generally, it has a slow course and often remains confined to the skin. Over time, in about 10% of cases, it can progress to the lymph nodes and internal organs.

Mentioned in: Corticosteroids, Systemic, Cutaneous T-Cell Lymphoma

---

mycosis fungoides

[fung·goi′dēz]

a rare chronic lymphomatous skin malignancy resembling eczema or a cutaneous tumor that is followed by microabscesses in the epidermis and lesions simulating those of Hodgkin's disease in lymph nodes and viscera. The condition is considered a distinctive entity by some specialists and a cutaneous manifestation of a malignant lymphoma by others.

---

mycosis [mi-ko´sis]

any disease caused by fungi.

mycosis fungoi´des a chronic or rapidly progressive form of cutaneous T-cell lymphoma (formerly thought to be of fungal origin), which in some cases evolves into generalized lymphoma. It may be divided generally into three successive stages: premycotic, associated with intensely pruritic eruptions; infiltrated plaques, or mycotic, characterized by the presence of abnormal mononuclear cells (Sézary cells); and mushroom-like tumors that often ulcerate. The tumor stage (d'emblée type) may develop without preceding lesions or prodromal symptoms.

opportunistic mycosis a fungal or funguslike disease occurring as an opportunistic infection. Fungi that may become opportunistic pathogens include species of Aspergillus, Candida, Mucor, and Cryptococcus. Successful treatment of opportunistic mycoses depends on identification of the specific organism causing the infection. Without effective therapy a systemic infection of this type can be fatal.

---

mycosis fungoides,

n a rare, chronic, lymphomatous skin malignancy resembling eczema or a cutaneous tumor that is followed by microabscesses in the epidermis and lesions simulating those of Hodgkin disease in lymph nodes and viscera.

---

mycosis

pl. mycoses; any disease caused by fungi.

---

dermal mycosis

see ringworm, epizootic lymphangitis, sporotrichosis, swamp cancer. Called also dermatophytosis.

mycosis fungoides

a chronic, malignant, lymphoreticular neoplasm of the skin, and, in late stages, lymph nodes and viscera; a type of cutaneous lymphosarcoma involving T lymphocytes. It occurs in humans, dogs and cats.

guttural pouch mycosis

see guttural pouch mycosis.

opportunistic mycosis

a fungal or fungus-like disease occurring in an animal with a compromised immune system. Opportunistic organisms are normal resident flora that become pathogenic only when the host's immune defenses are altered, as in immunosuppressive therapy, in a chronic disease, such as diabetes mellitus, or during steroid or antibacterial therapy that upsets the balance of bacterial flora in the body.

superficial mycosis

those involving the superficial layers of the skin; typical of infections caused by dermatophytes.

systemic mycosis

fungal infection spread via the bloodstream and characterized by multiple granulomatous lesions in many organs. See aspergillosis, blastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, mucormycosis.

---

mycosis fungoides  

Hematology A rare–0.3/105/yr, malignant lymphoproliferation of paracortical T cells, usually helper, less often, suppressor subtypes that is 2-fold more common in older blacks Clinical Skin involvement precedes Sx by up to 2 yrs; the leukemic phase–Sezary syndrome–occurs in 80% and is accompanied by fever, weight loss, lymphadenopathy, hepatosplenomegaly, lung involvement, eosinophilia, lymphocytosis, peripheral neuropathy, and periarteritis nodosa. Stages of ↑ aggression: Erythema stage, plaque stage, tumor stage, d'emblee stage Management Early RT and chemotherapy don't alter clinical disease