mycobacterium simiaeA mycobacterium, first isolated from rhesus macaques in 1965. It is a slow-growing photochromogen, appearing rust-coloured after exposure to light, and is the only nontuberculous mycobacterium that, like M tuberculosis, is niacin positive. Most isolates of M simiae have been reported from the southwestern US, Cuba and Israel. Its environmental niche is believed to be aquatic.
M simiae infection most commonly occurs in HIV-positive patients with pulmonary disease as well as lymphadenopathy, skin lesions and genitourinary tract involvemen. M simiae may cause infection (e.g., regional lymphadenopathy) in immunocompetent hosts.
Isoniazid, rifampin, ethambutol.
My·co·bac·te·ri·um sim·i·ae(mī'kō-bak-tēr'ē-ŭm sim'ē-ē)
A slow-growing, photochromogenic, acid-fast bacillus; rarely associated with pulmonary disease in humans.