Muir-Torre syndrome


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Tor·re syn·drome

(tor'ē),
multiple sebaceous gland adenomas associated with multiple visceral malignancies, often colorectal carcinoma.
Synonym(s): Muir-Torre syndrome

Tor·re syn·drome

(tor'ē),
multiple sebaceous gland adenomas associated with multiple visceral malignancies, often colorectal carcinoma.
Synonym(s): Muir-Torre syndrome

Muir-Torre syndrome

(myo͝or′tôr′ā, -ē)
n.
An autosomal dominant condition characterized by multiple tumors of the sebaceous glands and one or more visceral malignancies, especially of the gastrointestinal tract.

Muir-Torre syndrome

A rare autosomal-dominant condition, formally defined as > 1 sebaceous skin tumour (e.g., sebaceous proliferation, sebaceoma), and > 1 internal (visceral) malignancy (e.g., colorectal, bladder, renal pelvis, breast, endometrial, haematologic, lung).
 
The skin tumours that develop in MTS are atypical and low-grade, not metastatic, and are cured by excision.

Muir-Torre syndrome

A condition characterized by multiple internal CAs–colon, bladder, lung, sebaceous proliferation, and keratoacanthomas

Muir,

Edward G., English surgeon, 1906-1973.
Muir-Torre syndrome - Synonym(s): Torre syndrome

Torre,

Douglas P., U.S. dermatologist, 1919–.
Muir-Torre syndrome - Synonym(s): Torre syndrome
Torre syndrome - multiple sebaceous gland neoplasms associated with multiple visceral malignancies. Synonym(s): Muir-Torre syndrome
References in periodicals archive ?
MSH6 mutation in a family affected by Muir-Torre syndrome.
Screening for Muir-Torre syndrome using mismatch repair protein immunohistochemistry of sebaceous neoplasms.
Bruckschwaiger, "Transitional cell carcinoma in the Muir-Torre syndrome," The Journal of Urology, vol.
An awareness of the potential for associated malignancies as a component of Muir-Torre Syndrome is necessary to appropriately workup and manage such patients.
Association of sebaceous gland tumors and internal malignancy: the Muir-Torre syndrome.
Muir-Torre Syndrome (MTS) is a rare autosomal-dominant disorder, described independently by Muir, Yates Bell, Barlow (1) and Torre (2) that is characterized by the predisposition to both sebaceous neoplasms and internal malignancies.
The Muir-Torre syndrome in kindreds with hereditary nonpolyposis colorectal cancer (Lynch syndrome): A classic obligation in preventive medicine.
Microsatellite instability and Expression of hMLH-1 and hMSH-2 in sebaceous gland carcinomas as markers for Muir-Torre syndrome.
Spectrum of genetic alterations in Muir-Torre syndrome is the same as in HNPCC.
Microsatellite instability and mismatch repair protein expression in sebaceous tumors, keratocanthoma, and basal cell carcinomas with sebaceous differentiation in Muir-Torre syndrome.
323,331) Loss of hMSH2 or hMLH1 expression in sebaceous neoplasms, as demonstrated by immunohistochemistry, is suggestive of Muir-Torre syndrome.
Clinicopathological relevance of the association between gastrointestinal and sebaceous neoplasms: the Muir-Torre syndrome.