AMH

(redirected from Muellerian-inhibiting substance)

AMH

A gene on chromosome 19p13.3 that encodes anti-Müllerian hormone, a member of the transforming growth factor-beta gene family, which mediates male sexual differentiation. AMH causes regression of Müllerian ducts, which would otherwise differentiate into the uterus and fallopian tubes.
 
Molecular pathology
AMH mutations result in persistent Müllerian duct syndrome.