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Muellerian duct |
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müllerian duct, Muellerian duct either of the paired embryonic paramesonephric ducts developing into the vagina, uterus and uterine tubes, and becoming largely obliterated in the male or retained as the uterus masculinus or prostatic utricle. Named after J.P. Müller, a German physiologist. müllerian duct aplasia the ovaries cycle normally and the lumen of the tube oral to the obstruction distends with secreted fluids. The lumen may be obstructed at any location along its length, including only one horn; the commonest form is hymenal persistence. Called also 'white heifer disease'. müllerian duct inhibitory factor produced by the Sertoli cells in the developing testis; causes müllerian duct regression, a key step in sexual differentiation. |
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