moyamoya disease

(redirected from Moya moya)

moy·a·moy·a dis·ease

[MIM*252350] Because moyamoya is not a proper name, it is spelled with a lowercase m.
A cerebrovascular disorder occurring predominantly in the Japanese, in which the vessels of the base of the brain become occluded and revascularized with a fine network of vessels; it occurs commonly in young children and is manifested by convulsions, hemiplegia, mental retardation, and subarachnoid hemorrhage; the diagnosis is made by the angiographic picture.
[Jap. addlebrained]

moyamoya disease

[moi′əmoi′ə]
a cerebrovascular disorder in which the main cerebral arteries at the base of the brain are replaced by a fine network of vessels. It is caused by progressive stenosis of the large-caliber vessels and development of collateral network. It tends mainly to affect Japanese children and young adults and is characterized by convulsions, hemiplegia, mental retardation, and subarachnoid hemorrhage. Patients who survive into adulthood are susceptible to massive intracerebral hemorrhage caused by rupture of the fragile network of new vessels. Few patients live beyond 30 years of age.

moyamoya disease

An idiopathic disease pattern characterised by bilateral stenosis of the internal carotid arteries, accompanied by a network of abnormal collateral vessels that bypass the stenosis. It is named for the “smoky” (in Japanese, moya-moya) angiographic appearance of prominent collateral vessels of the basal ganglia that accompany narrowed and distorted cerebral arteries with thin collateral vessels, which arise from the circle of Willis, with progressive occlusion.
 
Clinical findings
Moyamoya disease is more common in females who are presenting as TIAs. Initially described in the Japanese and characterised by a familial tendency, it is also well described in Caucasians. It may follow a febrile illness and present with an abrupt onset of hemiparesis, transient aphasia and convulsions,

DiffDx, “puff of smoke” pattern
Occlusive intracranial atherosclerosis, radiation arteritis, intravascular tumour proliferation, tuberculous meningitis.
 
Management
Revascularisation using the parietal branch of the superficial temporal artery.
References in periodicals archive ?
Moya moya disease in children usually presents with transient ischemic attack or recurrent stroke and prognosis is variable.
Child was investigated for possibility of sickle cell anemia, neurofibromatosis and Moya moya disease.
DISCUSSION: Moya moya disease is a chronic progressive non-atherosclerotic non-inflammatory non-amyloid occlusive intracranial vasculopathy of unknown cause.
E n relacion con la nota El avionazo, asunto politico, publicada en el numero 1685 de la revista Proceso, me permito senalar, una vez mas, que el senor Jose Luis Moya Moya ni trabaja ni ha trabajado para mi en ninguna condicion o circunstancia.
Marie Lochrie, 17, has moya moya, which affects one in two million and causes repeated strokes.
Proceeds from the 1998 event will be used to establish the Violet Loh Moya Moya Research Grant.
Little research has been done in the area of Moya Moya.
Takahashi, Magnification angiography in Moya Moya disease.
IMAGE 1: MRI: revealed presence of infarction in the bilateral frontal lobes as classic for a paediatric moya moya.
La primera denuncia la presento el 2 de diciembre pasado, en su "caracter de ciudadano", Jose Luis Moya Moya, senalado como asesor del senador panista Federico Doring y como una fuente mas del "fuego amigo" que, dentro del blanquiazul, se esta lanzando contra Santiago Creel para bloquear su carrera politica.
Anita Redmond, 20, and Elizabeth Carty, nine, were diagnosed with Moya Moya Syndrome two years ago.
Two neighbours would have more chance of winning the Lotto than contracting Moya Moya Syndrome.