monokine


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monokine

 [mon´o-kīn]
any of various soluble mediators of immune responses that are not antibodies or complement components and that are produced by mononuclear phagocytes (monocytes or macrophages).

mon·o·kine

(mon'ō-kīn),
Cytokines secreted by both monocytes and macrophages. These substances influence the activity of other cells. See: cytokine.
[monocyte + G. kineō, to set in motion]

monokine

/mono·kine/ (mon´o-kīn) a general term for soluble mediators of immune responses that are not antibodies or complement components and that are produced by mononuclear phagocytes (monocytes or macrophages).

monokine

a cytokine produced by macrophages that act on T lymphocytes to enhance cell-mediated immunity, e.g. interleukin 1.
References in periodicals archive ?
4] Nonstandard abbreviations: 2D-PAGE, 2-dimension polyacrylamide gel electrophoresis; MBL, mannose-binding lectin; TBS, tris-based saline; MCP, monocyte chemoattractant protein; MIG, monokine induced by gamma-interferon; MIP, macrophage inflammatory protein; TNF, tumor necrosis factor; TECK, thymus expressed chemokine; IFN, interferons; IL, interleukin; TGF, transforming growth factor; CNTF, ciliary neutropic factor; EGF, epidermal growth factor; ICAM, intercellular adhesion molecule; IGFBP, insulin-like growth factor binding proteins; BMP, bone morphogenetics protein.
17) studied 88 SARS patients with the same chemokine panel bead array assay and confirmed activation of chemokines, including IP-10, monokine induced by interferon-[gamma] (MIG), and monocyte chemoattractant protein-1 (MCP-1).
For instance: a) LPSs are powerful molecular tools to study a variety of cellular activation mechanisms involving the production of lymphokines and monokines (e.
While GPE inhibited the monocytes/macrophage response, propolis decreased both monokines and interferon [gamma] (IFN[gamma]) production.
Under the definition of peptide hormones superfamily, they are defined as the intercellular messengers like adipokines (adiponectin, leptin, resistin), cytokines (chemokines, hematopoietic growth factors, hepatocyte growth factor, interferons, interleukines, lymphokines, monokines, osteopontin, transforming growth factor beta, TNF), endothelial growth factors, endothelins, fibroblast growth factor, quinines (bradykinin, kininogens, tachykinin) and platelet derived growth factor (see, http://www.
Immune system cells function is regulated by the action of specific molecules called cytokines, mainly lymphokines and monokines.
Cytokines--Include lymphokines, monokines, and other polypeptides that regulate immunologic, inflammatory, and reparative host responses.
Machophage function in alloxan diabetic mice: expression of cadhesion mollecules, generation of monokines and oxygen and NO radicals.
Interactions of immunoreactive monokines (interleukine-1 and tumor necrosis factor) in the bivalve mollusc Mytilus edulis.
Distinct sets of acute phase plasma proteins are stimulated by separate human hepatocyte-stimulating factors and monokines in rat hepatoma cells.
Important mediators of mucosal inflammation and resultant ulceration include oxygen free radicals, lymphokines, and monokines (1).