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monokine

   Also found in: Encyclopedia, Wikipedia 0.01 sec.
monokine /mono·kine/ (mon´o-kīn) a general term for soluble mediators of immune responses that are not antibodies or complement components and that are produced by mononuclear phagocytes (monocytes or macrophages).
monokine [mon´o-kīn]
any of various soluble mediators of immune responses that are not antibodies or complement components and that are produced by mononuclear phagocytes (monocytes or macrophages).

monokine
a cytokine produced by macrophages that act on T lymphocytes to enhance cell-mediated immunity, e.g. interleukin 1.


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Monokine induced by interferon gamma and IFN-gamma response to a fusion protein of Mycobacterium tuberculosis ESAT-6 and CFP-10 in Brazilian tuberculosis patients.
Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression.
J Clin Invest 101: 643-649 Itoh Y, Okanoue T, Sakamoto S, Nishioji K, Yasui K, Sakamoto M, Kashima K (1995) Monokine production by peripheral whole blood in chronic hepatitis C patients treated with interferon.
 
 
 
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