monoclonal /mono·clo·nal/ (-klōn´al)
Monoclonal
monoclonal
monoclonal [mon″o-klo´nal]
1. derived from a single cell.
2. pertaining to a single clone.
mon·o·clo·nal (m n  -kl  nl)n. Of or relating to a protein from a single clone of cells, all molecules of which are the same, as in the Bence-Jones protein. |
Monoclonal
Identical cells or proteins; cells (clones) derived from a single, genetically-distinct cell, or proteins produced by these cells.
monoclonal
[mon′əklō′nəl]
Etymology: Gk, monos + klon, twig
pertaining to or designating a group of identical cells or organisms derived from a single cell or organism. Compare polyclonal.
monoclonal [mon″o-klo´nal]
derived from a single cell; pertaining to a single clone.
monoclonal
derived from a single cell; pertaining to a single clone.
monoclonal antibodies
identical immunoglobulin molecules formed by a single clone of plasma cells; may occur naturally in plasma cell myelomas or in vitro by the fusion of an antibody producing B lymphocyte with a non-antibody-producing myeloma B cell. The fused heterokaryon has the properties of immortality and production of a monoclonal antibody. For the most part, monoclonal antibodies are made in mouse systems.
monoclonal gammopathy
see monoclonal gammopathy.
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