monobactam

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mon·o·bac·tam

(mon'ō-bak'tam),
A class of antibiotic that has a monocyclic β-lactam nucleus and is structurally different from other β-lactams; for example, aztreonam.

monobactam

/mon·o·bac·tam/ (-bak´tam)
1. a class of synthetic antibiotics with a cyclic beta-lactam nucleus.
2. a class of synthetic antibiotics having a monocyclic β nucleus.

mon·o·bac·tam

(mon'ō-bak'tam)
Antibiotic that has a monocyclic β-lactam nucleus and is structurally different from other β-lactams.

mon·o·bac·tam

(mon'ō-bak'tam)
Class of antibiotic with a monocyclic β-lactam nucleus: structurally different from other β-lactams.

monobactam

a group of monocyclic β-lactamase resistant antibiotics which includes aztreonam and carumonam sodium.
References in periodicals archive ?
aureus Antibiotics (n = 36) (n = 12) (n = 6) S R S R S R Penicillin 30 6 8 4 6 0 Carbapenems 36 0 12 0 6 0 Quinolones 18 18 7 5 6 0 Monobactams 26 10 7 5 3 3 Cephalosporins 10 26 4 8 4 2 Aminoglycosides 18 18 10 2 6 0 Glycopeptides 0 36 0 12 6 0 Macrolides 0 36 0 12 2 4 Pseudomonas Proteus S.
The [beta]-lactam antibiotics include the cephalosporins, the monobactams, the penems, the carbapenems, as well as penicillin.
ESBLs are also able to hydrolyze three and four generation cephalosporins and monobactams.
Beta-lactamases are the bacterial enzymes produced by a number of bacteria that provide resistance to beta-lactam antibiotics which include penicillins, carbapenems, cephalosporins and monobactams.
Sterile and high potency APIs, steroids, generics, monobactams, boronic acids and controlled substances
Strategically, our acquisitions have helped us establish a vast and responsive global development and manufacturing network, an extensive portfolio of unique APIs that have high barriers to entry, and expanded technical capabilities in areas such as sterile API, fermentation and monobactams that complement our organic business.
Enzymes that catalyze the cleavage of p-lactam rings in penicillins, cephalosporins, monobactams, and carbapenems were first described by Abraham and Chain in 1940.
ESBLs are capable ofefficiently hydrolyzing penicillin, cephalosporin, the oxyimino group containingcephalosporins (cefotaxime, ceftazidime) and monobactams (aztreonam) and wide range of class A ESBLs have been reported in Acinetobactersp.
3,5,16] Colistin is usually combined with sulbactam, cephalosporins, carbapenems, piperacillin-tazobactam, monobactams, aminoglycosides, fluoroquinolones, rifampin, tetracyclines and tigecycline.
Like most carbapenemases, KPCs are enzymes which inactivate all beta-lactam antibiotics, including carbapenems, penicillins, cephalosporins and monobactams.
Other [beta]-lactam antibiotics: [beta]-Lactamase inhibitors, carbapenems, and monobactams.