model organism

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model organism

A generic term for an organism used in research.

model organism

a laboratory organism that has many advantages for experimental research. Examples include Arabidopsis thaliana (mustard plant), Caenorhabditis elegans (NEMATODE worm), Chlamydomonas reinhardtii (unicellular alga), Dictyostelium discoideum (SLIME MOULD), Drosophila melanogaster (FRUIT FLY), ESCHERICHIA COLI (BACTERIUM),Mus musculus (Mouse), XENOPUS LAEVIS (African clawed frog) and YEAST (SACCHAROMYCES cerevisiae, and other species). See also HUMAN GENOME PROJECT.
References in periodicals archive ?
This project would provide one of the first examples of next-generation technologies for whole-organism drug screening, with the potential of paving the way for the widespread use of worms and other alternative model organisms for the replacement, reduction and refinement of animal testing in biomedical research and pharmaceutical industries.
Then, the researchers mimicked these mechanisms in somatic tissues of model organisms to extend lifespan and delay age-related diseases.
It was reported yesterday that the transaction provides Knudra with global access to ERS Genomics' CRISPR-Cas9 genome editing intellectual property for use in engineering of model organisms.
Biologists present a thorough reference on crayfish for scientists who want to study them as model organisms or explore their role in the environment, and for readers interested in raising them for food or other purposes.
It contains a federally endangered putative alloployploid of unknown parental origin, and it can serve as a rich resource for the in situ and in silico validation of the valuable findings generated by study of traditional model organisms.
The book is divided into five sections: Section I covers proteomics and the transcriptome; section II deals with the various networks in living things such as the interactome, gene regulatory networks, networks of genes, and the value of graph theory in analyzing cells; section III emphasizes the flows of information through a cell and the use of mathematical models of intracellular processes; section IV discusses the creation and validation of quantitative models of stem cell differentiation as well as the systems biology of several model organisms such as yeast, C.
Samples are available isolated from hundreds of different source tissues, including human normal and diseased tissues, as well as a variety of genetic model organisms including mouse, rat, primates and plant species.
These approaches bypass the need for the difficult and time-consuming task of mapping causative mutations by genetic crosses as used in model organisms.
Understanding regeneration in model organisms gives hope that it may one day be possible for amputees to regrow limbs or for heart attack patients to regrow healthy heart muscle.
For researchers working with anaerobic protozoa and related organisms, and eukaryotic model organisms, Clark (infectious and tropical diseases, London School of Hygiene and Tropical Medicine, UK) et al.
The principal way of doing that is with model organisms, namely mice.
The software comes with the ResNet Mammalian Database with access to other databases, including ResNet Plant, and enables pathway analysis for most model organisms.

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