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This last finding is "difficult to explain," since heart failure is a chronic condition, and the studies had limitations, which "make it difficult to determine whether excess heart failure was related to Mirapex use or other influencing factors," the FDA statement said.
Mirapex, for example, is the subject of a multidistrict litigation action in Minnesota and a Canadian class action which allege the drug can cause compulsive behaviors, including pathological gambling.
Mirapex (pramipexole), manufactured by Germany-based Boehringer Ingelheim Pharmaceuticals and Pfizer, Inc.
And the man, from Bangor, Co Down, is planning to sue the firm behind the medication Mirapex which he said has ruined his life.
Although there is no cure for Parkinson's, there are a number of highly effective medications, including Parlodel, Permax and Mirapex, that can significantly improve a patient's level of functioning.
Doctors also sometimes prescribe Neurontin or Mirapex (developed for Parkinson's disease) to ease symptoms.
A daily dose of Mirapex (generic name: pramipexole) improved symptoms of restless legs syndrome (RLS) for a 24-hour period and produced significant improvements in patients' sleep, according to study results presented at a meeting of the Movement Disorder Society.
c) Mirapex ER and Pramipexole, Requip XL and Ropinirole
Requip and Mirapex are oral medications approved by the FDA for the treatment of RLS and are typically administered daily before bedtime but can also have a split dosage time with part of the dose in the late afternoon/early evening and the other at bedtime.
The introduction of Mirapex and Requip has been largely responsible for driving the market over the recent period.
Canonsburg PA) persuaded a judge to invalidate a patent for the Parkinson's disease medicine Mirapex that is owned by a U.