DYRK1B

(redirected from Minibrain-related kinase)

DYRK1B

A gene on chromosome 19q12-q13.1 that encodes a dual-specificity kinase with both serine/threonine and tyrosine kinase activities. DYRK1B enhances transcriptional activity of TCF1/HNF1A and FOXO1 and inhibits epithelial cell migration; it mediates colon carcinoma cell survival in mitogen-poor environments.