meprobamate

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meprobamate

 [mĕ-pro´bah-māt, mep″ro-bam´āt]
an antianxiety agent and skeletal muscle relaxant; administered orally.

me·pro·ba·mate

(mĕ-prō'bă-māt mep'brō-bam'āt), Avoid the misspelling/mispronunciation meprobromate.
An oral anxiolytic with potential for dependency and addiction.

meprobamate

/me·pro·ba·mate/ (mĕ-pro´bah-māt) (mep″ro-bam´āt) a carbamate derivative with tranquilizing and muscle relaxant actions.

meprobamate

(mĕp′rō-băm′āt′, mĕ-prō′bə-)
n.
A bitter white powder, C9H18N2O4, used as a tranquilizer, muscle relaxant, and anticonvulsant.

meprobamate

[miprō′bəmāt]
an antianxiety agent.
indications It is prescribed in treatment of anxiety and tension.
contraindications Intermittent porphyria, CNS depression, narrow-angle glaucoma, pregnancy, or known hypersensitivity to this drug or to the chemically related drug carisoprodol prohibits its use.
adverse effects Among the most serious adverse effects are exacerbation of intermittent porphyria, augmentation of effects of other central nervous system depressants, and various allergic reactions. Drowsiness and ataxia commonly occur.

meprobamate

A potentially addicting agent that blocks spinal interneurons, which has anticonvulsant, anxiolytic, muscle-relaxing, sedative, hypnotic and tranquilising properties.

Adverse effects
Hypotension, depression of brainstem activity, coma, death.
 
Metabolism
Liver; excreted in urine, stool.

Therapeutic range
5–30 µg/mL.
 
Toxic range
> 60 µg/mL.
 
Specimen
Serum.
 
Method
TLC, GC, colorimetry.

meprobamate

Pharmacology A potentially addicting agent with anticonvulsant, anxiolytic, muscle relaxing, sedative, hypnotic, tranquilizing properties that blocks spinal interneurons, depressing brainstem functions, coma, death; may cause hypotension Metabolism Liver; excreted in urine, stool. See Therapeutic drug monitoring.

me·pro·ba·mate

(mĕ-prō'bă-māt) Avoid the misspelling/mispronunciation meprobromate.
An oral anxiolytic with potential for dependency and addiction.

meprobamate

A mildly tranquillizing carbamate drug with muscle-relaxant properties used in combination with painkilling drugs to treat muscle and joint pain. A brand name is Equagesic.

me·pro·ba·mate

(mĕ-prō'bă-māt)
Oral anxiolytic with potential for dependency and addiction.

meprobamate

(məprō´bamāt´),
n brand names: Equanil, Miltown, Probate, Trancot;
drug class: sedative-hypnotic, anxiolytic (Controlled Substance Schedule IV);
action: nonspecific central nervous system depressant; acts in thalamus, limbic system, and spinal cord;
use: anxiety disorders.

meprobamate

a tranquilizer and skeletal muscle relaxant.