Million Women Study

Million Women Study

A national study involving more than one million UK women aged 50 and over, which is a collaboration between Cancer Research UK and the NHS, partly funded by the Medical Research Council and Health and Safety Executive (UK Government). While the primary focus is on the effects of hormone replacement therapy (HRT) use, the large size of the study allows other questions to be asked, including how various reproductive and lifestyle factors affect older women’s health. The MWS is also assessing how diet, exercise, employment patterns, oral contraceptive use, childbirth and breastfeeding, and family history of illness impact on cancer and to other conditions such as fractures, gallbladder disease and cardiovascular disease.

Conclusion
For every 10,000 women on oestrogen for 10 years, there will be 5 extra breast cancers, and 19 extra cancers in women receiving combined HRT.
Mentioned in ?
References in periodicals archive ?
The British Journal of Cancer published a remarkable study in 2014, a large prospective study of women in the United Kingdom, known as the Million Women Study, which looked at organic food consumption.
In the British Million Women Study, one drink a day increased women's risk of breast cancer by 12 percent, with even three to six drinks weekly posing some risk.
The researchers based their conclusion on data from the Million Women Study in Britain, and it contradicts a large body of research, not to mention conventional wisdom.
Of course people who are ill tend to be unhappier than those who are well, but the UK Million Women Study shows that happiness and unhappiness do not themselves have any direct effect on death rates.
The largest study so |far on mobile phones and cancer is part of the Million Women Study and included around 790,000 women.
1 million women in the United Kingdom with no history of cancer, heart disease, stroke, blood clots, or diabetes who joined the Million Women study in 1996-2001.
The volunteers, all aged 50 and over, will have already been recruited to existing population-scale studies such as UK Biobank and the Million Women Study.
Sweetland S, Beral V, Balkwill A, et al; The Million Women Study Collaborators.
A trio of studies - the Collaborative Reanalysis (CR); the Women's Health Initiative (WHI); and the Million Women Study (MWS) - prompted the use of HRT to tumble, starting in 2002, after they concluded that it causes breast cancer.
The authors of the Million Women Study wrote in The Lancet medical journal: "Smokers lose at least 10 years of lifespan.
It comes as the Million Women Study found female smokers who give up before they are 30 will undo 97 per cent of the damage done to them so far.