microsatellite(redirected from Microsatellite DNA)
Also found in: Dictionary.
Related to Microsatellite DNA: Minisatellite DNA, microsatellite analysis, Microsatellite instability, Simple Sequence Repeats
1. A short sequence of DNA consisting of multiple repetitions of a set of two to nine base pairs, used as a genetic marker when individuals differ in the number of repetitions.
2. A small artificial satellite, usually with a mass of less than 100 kilograms (220 pounds) when deployed in orbit.
microsatelliteA highly polymorphic segment of DNA composed of repetitive stretches of short sequences of 2–6 base pairs of DNA, which serve as genetic markers to track inheritance in families. Microsatellites include dinucleotides, trinucleotides and tetranucleotides, repeated in tandem arrays throughout a genome. The human genome has 50–100,000 microsatellite loci.
A section of DNA in which a unit of one to five nucleotides is repeated a variable number of times. Repeating trinucleotides that expand during meiosis are associated with Huntington's disease and fragile X syndrome.