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micrographia

   Also found in: Wikipedia 0.01 sec.
micrographia /mi·cro·graph·ia/ (mi″kro-graf´e-ah) tiny handwriting, or handwriting that decreases in size from normal to minute, seen in parkinsonism.


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Current knowledge of manganese neurotoxicity is based on occupational inhalation exposure, resulting in an extrapyramidal syndrome, characterized by symptoms of gait dysfunction with a propensity to fall backward, postural instability, bradykinesia, rigidity, micrographia, masked facies, speech disturbances, and muscle tremors.
Their hope, as Robert Hooke expressed it in his 1665 manifesto Micrographia, was that "by rectifying the operations of the Senses," these instruments would put knowledge on a new and more certain foundation.
Based on his findings and work, he published a book, Micrographia, in 1665, which featured observations both microscopic and telescopic as well as a number of original biological theories.
 
 
 
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