microcystin

(redirected from Microcystine)

microcystin

(mī-krō-sis'tin),
Those compounds produced by Microcystis aeruginosa: potent hepatotoxins and probable tumor promoters.

microcystin

Any toxic, cyclic, non-ribosomal peptide produced by cyanobacteria, which has anticholinesterase activity or causes severe liver injury through DNA damage by activating endonucleases and inhibiting inhibit protein phosphatases types 1 and 2A. Topical exposure to microcystins causes skin and eye irritation, rhinorrhoea, vertigo and fatigue; parenteral exposure may cause death after initial exposure, often due to intrahepatic haemorrhage and hypovolemic shock. An epidemic of microcystin-related death occurred at a haemodialysis centre in Brazil due to impure water.

microcystin

a group of toxic cyclic decapeptides, the hepatotoxins in some cyanobacteria. See also microcystis, anabaena, gloeotrichia, oscillatoria, nostoc rivulare.